The Ramada group is set to open a 200 bedroom hotel three miles to the east of Heathrow.
The Ramada London Heathrow will offer weekend room rates as low as £69 and will be linked to the airport by the Heathrow Hoppa shuttle service.
The hotel, situated on the Bath Road at Cranford, is scheduled to open on September 17, and will offer 24-hour room service, five air-conditioned meeting rooms plus a work station and flat screen TV in each guest room.